About peripheral T-cell lymphoma
Learn more about your cancer and see how ADCETRIS could help
The importance of CD30
ADCETRIS is a CD30-directed treatment. This means that it works by targeting cells that have CD30, a protein that can be found on cancer cells, including peripheral T-cell lymphoma cells.
Even though CD30 is not usually found on healthy cells, ADCETRIS may affect them and cause side effects.
If your cancer cells have CD30, you may benefit from treatment with ADCETRIS.
Testing for CD30 protein
Depending on your T-cell lymphoma diagnosis, your doctor may order a test to find out how much CD30 is on your cancer cells. In some cases, the test result may be negative, meaning that your doctor may conclude that CD30 protein was not found. In reality, the amount of CD30 may just be very low.
If your doctor says that the CD30 test results are negative, ask them to check if there is any CD30 protein present on your cancer cells, no matter how low.
Relapsed primary cutaneous anaplastic large cell lymphoma and mycosis fungoides
Primary cutaneous anaplastic large cell lymphoma (pcALCL) and mycosis fungoides (MF) are 2 different types of cutaneous T-cell lymphoma, a type of blood cancer that involves the skin.
- Mycosis fungoides is the most common type of cutaneous T-cell lymphoma, occurring in about 50% of cases
- Primary cutaneous anaplastic large cell lymphoma happens less often
If your cancer has come back, there are still treatments that can help.
See how ADCETRIS worked in adults with relapsed primary cutaneous anaplastic large cell lymphoma or CD30-expressing mycosis fungoides.
Relapsed systemic anaplastic large cell lymphoma
Systemic anaplastic large cell lymphoma (sALCL) is a fast-growing type of T-cell lymphoma. It may appear in the skin, lymph nodes, bones, soft tissues, lungs, or liver. Its cancer cells have CD30 protein on them.
Anaplastic large cell lymphomas comprise about 1% of all non-Hodgkin lymphomas and about 10-20% of all T-cell lymphomas.
If your cancer comes back after combination chemotherapy, there are treatments that can help.
See how ADCETRIS worked in adults with relapsed systemic anaplastic large cell lymphoma.
Glossary
Relapse: When cancer has returned after a period of remission.
Remission: When signs and symptoms of cancer are reduced or undetectable.